Ozempic, a drug accepted to deal with sort 2 diabetes, is an efficient method to drop some pounds as nicely. Here is an inventory of celebrities who’ve admitted to utilizing this weight reduction drug.
Is Ozempic for weight reduction useful? A host of Hollywood celebrities have admitted to utilizing Ozempic, which has develop into extensively fashionable amongst individuals who need to drop some pounds. It is likely one of the manufacturers with semaglutide because the energetic ingredient to handle sort 2 diabetes. Despite the fact that the US Meals and Drug Administration has accepted this remedy solely to handle blood sugar ranges in individuals with sort 2 diabetes, the injectable remedy has gained reputation as a weight reduction drug. It’s not simply influencers and actuality TV stars who’ve experimented with it. Hollywood celebrities like Amy Schumer and Insurgent Wilson have additionally admitted to utilizing it to drop some pounds. However not everybody has had a constructive expertise.
Listed below are a number of the Hollywood celebrities who’ve admitted to utilizing Ozempic for weight reduction, and what they stated about its advantages or negative effects.
1. Lizzo
Singer and rapper Lizzo is the newest superstar to open up about utilizing the a lot talked-about weight reduction drug. Whereas discussing her weight reduction efforts, she revealed on the Simply Trish podcast in June 2025 that she had tried Ozempic. “It’s simply the science for me, energy in versus energy out. Ozempic works since you eat much less meals.” Explaining the way it works, she stated, “It makes you are feeling full, so for those who can simply do this by yourself and get thoughts over matter.”

2. Kathy Bates
Final yr, Oscar-winning actress Kathy Bates stated that she misplaced 80 kilos over the previous seven years by making way of life modifications. She then misplaced one other 20 kilos by taking Ozempic. “There’s been quite a lot of discuss that I simply was in a position to do that due to Ozempic. However I’ve to impress upon individuals on the market that this was arduous work for me, particularly through the pandemic. It’s very arduous to say you’ve had sufficient,” she advised Folks.
3. James Corden
Comic-actor-TV host James Corden stated that he tried Ozempic, but it surely was not very efficient for him. “I attempted Ozempic, and it gained’t be shocking to you whenever you take a look at me now, that it didn’t actually work,” Corden stated in one of many episodes of his podcast, This Lifetime of Mine with James Corden, in 2024. “I attempted it for a bit after which what I realised was I used to be like, ‘Oh no, nothing about my consuming has something to do with being hungry.’ All this does is make you are feeling not hungry.”
4. Amy Schumer
Actress and comic Amy Schumer bought sick after taking the burden loss drug. “I’ve this gene, GDF 15, which makes you extraordinarily vulnerable to nausea, which is why I used to be so sick throughout my being pregnant,” Schumer, who gave delivery to her son Gene in 2019, stated throughout The Howard Stern Present in January 2025. “So I attempted Ozempic virtually 3 years in the past, and I used to be like bedridden. I used to be vomiting. After which you don’t have any power.” She “misplaced 30 kilos so fast” and “seemed nice” after taking Ozempic, however she couldn’t elevate her “head off the pillow, so what’s the purpose?”
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5. Sharon Osbourne
TV persona Sharon Osbourne can be one of many celebrities who used Ozempic to assist handle her weight. “I misplaced 42 kilos now and it’s simply sufficient,” she stated throughout an episode of Piers Morgan’s podcast Piers Morgan Uncensored in 2023. “I didn’t really need to go this skinny, but it surely simply occurred and I’ll most likely put all of it on once more quickly.”
Speaking concerning the negative effects of Ozempic, she stated, “At first, I imply, you are feeling nauseous. You don’t throw up bodily however you’ve bought that feeling. I used to be about two, three weeks the place I felt nauseous the entire time. You get very thirsty and also you don’t need to eat. That’s it.” She doesn’t need children to get hooked to it. “You’ve bought to maintain these items away from youthful individuals as a result of they’ll go berserk on it, and it’s not proper,” she stated.

6. Insurgent Wilson
Actress Insurgent Wilson admitted to utilizing Ozempic for a while. “Somebody like me might have a bottomless urge for food for sweets, so I believe these medication may be good,” she stated throughout an interview with The Sunday Occasions in 2024. The Pitch Good actress, who now not makes use of Ozempic, stated, “Nobody aside from my mother wished me to drop some pounds. Folks thought I’d lose my pigeonhole in my profession, enjoying the fats humorous character, they usually wished me to proceed in that.”
7. Chelsea Handler
Comic Chelsea Handler talked about unknowingly being prescribed Ozempic. “So, my anti-aging physician simply arms it out to anyone. I didn’t even know I used to be on it,” stated Handler throughout her look on the podcast Name Her Daddy in 2023. Her physician advised her, “Should you ever need to drop 5 kilos, that is good.”
Chandler recalled giving herself a dose of the remedy after a trip. “I got here again from a trip and I injected myself with it. I went to lunch with a girlfriend just a few days later, and he or she was like, ‘I’m probably not consuming something. I’m so nauseous, I’m on Ozempic,’” she recalled. “And I used to be like, ‘I’m sort of nauseous too.’ However I had simply come again from Spain and was jet-lagged.” Handler’s good friend requested her if she was certain she wasn’t on Ozempic. The comic stated that she was simply “on semaglutide.” Her good friend defined, “That’s Ozempic.”
8. Kelly Osbourne
Singer and actress Kelly Osbourne, daughter of Ozzy and Sharon Osbourne, was all reward for Ozempic. “I believe it’s wonderful,” she stated concerning the remedy throughout an interview with E! Information final yr. “There are one million methods to drop some pounds, why not do it by means of one thing that isn’t as boring as understanding?”
9. Macy Grey
Grammy winner Macy Grey is likely one of the celebrities who didn’t have a superb expertise with Ozempic. “Oh, boy my abdomen hurts. I took Ozempic. I can’t go to the lavatory, and I used to be up all night time,” she stated throughout an episode of The Surreal Life: Villa of Secrets and techniques in 2024. On why she determined to strive Ozempic, she stated, “Quietly, I’m sort of a useless particular person. I’ve gained quite a lot of weight over the previous couple years, and that is proper concerning the time when everyone begins speaking about this Ozempic.”
10. Tori Spelling
Actress Tori Spelling revealed that she used two weight reduction medication — Ozempic and Mounjaro. “I did Mounjaro and everybody admits it now,” she stated throughout her Misspelling podcast in 2024. Earlier than that, she used Ozempic when she was at 160 kilos. “I attempted Ozempic and it didn’t work for me.”
11. Stephen Fry
English actor and comic Stephen Fry stated that he tried Ozempic years in the past. “I’m an early adopter of these items,” he stated throughout an episode of River Café Desk 4 podcast in 2024.
“I occurred to be in America, and I’d examine it, and I requested my physician in America, my doctor as they wish to name them, and he stated, ‘I believe I can get you some.’ He tried me on it, and the primary week or so, I used to be pondering, ‘That is astonishing. Not solely do I not need to eat, I don’t need any alcohol of any sort. That is going to be sensible.’” Then he began feeling sick. “I used to be actually throwing up 4, 5 instances a day and I believed, ‘I can’t do that.’ In order that’s it.”
A phrase of warning
Nausea, constipation and vomiting are a number of the widespread negative effects of Ozempic. Use this weight reduction drug solely after consulting a health care provider.