Mounjaro might assist to drop a few pounds, however it could actually additionally have an effect on your bowel actions. Let’s discover out the connection between Mounjaro and constipation.
Mounjaro is likely one of the diabetes medicine that may hold blood sugar below management and likewise assist folks to drop a few pounds. These two are the important thing advantages of this injectable medication, but it surely additionally has potential unwanted effects on the physique. Constipation is one such well being problem. Utilizing Mounjaro to handle kind diabetes or drop kilos might have an effect in your bowel actions. It may make your stools more durable, so it’s possible you’ll find yourself struggling on the bathroom. Fortuitously, there are some things you are able to do to get aid from constipation.
What’s Mounjaro?
Mounjaro is the model title of tirzepatide, a drugs that is available in a pre-filled pen. It’s a blood sugar-lowering treatment that’s usually prescribed to folks with kind 2 diabetes. “This medication works by activating two receptors known as GLP-1 (glucagon-like peptide-1) and GIP (Gastric Inhibitory Polypeptide), which enhance the physique’s ranges of incretins (intestine hormones),” shares endocrinologist Dr Sandeep Kharb. It really works by stimulating your physique’s manufacturing of insulin at any time when wanted. It additionally limits the amount of sugar produced by the liver and slows down digestion, serving to in lowering blood sugar ranges.
The US Meals and Drug Administration recommends it to handle blood sugar ranges in adults with kind 2 diabetes, and never for kind 1 diabetes or weight reduction. The beginning dosage is 2.5 mg that must be injected subcutaneously within the stomach, thigh or higher arm as soon as every week. After 4 weeks, the dosage may be elevated to five mg. The utmost dosage of this medication is 15 mg.
Mounjaro and constipation: A facet impact of this diabetes drug
In March 2025, the FDA shared that it obtained adversarial occasion stories that could be associated to folks utilizing tirzepatide in doses past what has been accepted by the company. In line with the company, folks skilled signs like vomiting, diarrhea, constipation and stomach ache. “Constipation is an anticipated adversarial impact of Mounjaro,” says Dr Kharb.
Right here’s how Mounjaro and constipation could also be linked:
- Decreased intestinal motion: This might help management your blood sugar and hold you full for a very long time, however decreased intestinal motion may contribute to constipation.
- Decreased urge for food: There could also be a hyperlink between Mounjaro and constipation, as this treatment can scale back urge for food. “If you happen to don’t eat or drink water a lot, it could actually result in much less fibre and fluid consumption,” says the professional. Fibre is a nutrient that helps to bulk up poop and make it simpler to move. Then again, ample fluid consumption is essential, because it helps to melt stools.
- Adjustments in absorption of fluids: Whereas taking this medication, water in your stools might get absorbed, leading to firmer, extra difficult-to-pass stools.
Mounjaro and constipation: The right way to get aid?
Mounjaro and constipation could also be linked, however don’t fear, you possibly can take easy steps to get aid. You simply should concentrate on easy way of life changes.
1. Keep hydrated
Be certain to have an ample quantity of water to assist soften your stools and promote common bowel actions. You simply have heard of individuals emphasising on consuming between 8 and 10 glasses of water every day. Nicely, this wholesome behavior might help to melt stools and make your bowel actions common.
2. Get transferring
“Constipation may be prevented and handled by common bodily exercise, comparable to strolling or swimming,” says the professional. Strolling, particularly after meals, helps digestion by stimulating intestinal exercise. This might help in stopping sluggish motion within the intestine.
3. Say sure to fiber
Fiber is not only essential to handle weight. “Going for a high-fiber weight-reduction plan can improve your stool bulk and enhance bowel regularity,” says the professional. Together with greens, have kidney beans, chia seeds and prunes for constipation administration, as they’re all wealthy in fibre.
4. Medicines
There are stool softeners that may assist you get aid from constipation. A few of the drugs embrace magnesium citrate, docusate sodium, magnesium citrate and polyethylene glycol. Checking with a health care provider relating to these drugs and their simply accessible varieties is a should.
What are the unwanted effects of Mounjaro for digestion?
Other than the Mounjaro and constipation connection, it might have an effect on your digestive well being in several methods. Different unwanted effects of Mounjaro for digestion embrace:
- Nausea
- Vomiting
- Indigestion
- Diarrhea
“These are sometimes extra intense whereas beginning the treatment or growing its dosage. Over time, your physique will be capable to adapt. And so, tolerance develops, resulting in a discount in symptom severity,” says Dr Kharb.
Nevertheless, sure meals and drinks can worsen these points. “Oily and spicy meals are inclined to irritate the digestive system, prolonging discomfort and triggering acid reflux disorder. Additionally, aerated drinks contribute to fuel buildup and acidity, aggravating indigestion,” says the professional.
Mounjaro long-term unwanted effects
Whereas there’s a hyperlink between Mounjaro and constipation, taking the treatment to handle kind 2 diabetes and drop a few pounds might result in extra unwanted effects. The checklist consists of nausea and acute pancreatitis. It’s best to seek the advice of a health care provider relating to the injectable treatment and dosage.
- It might result in muscle loss, as weight discount impacts fats in addition to muscle mass.
- Acute pancreatitis, a situation that happens when the pancreas will get swollen up and turns into infected in a brief time frame, is a uncommon however documented facet impact of tirzepatide (Mounjaro), as per analysis printed in Cureus.
- There’s a chance of gallstones.
Associated FAQs
What’s the greatest fibre complement for Mounjaro?
Incorporating complete grains, fruits, greens, and beans into your weight-reduction plan is one of the best ways to help your digestive well being. These meals assist by growing fibre consumption and selling common bowel actions. You may as well go for a fibre complement like Metamucil, however seek the advice of a health care provider first.
Can you are taking laxatives whereas on Mounjaro?
Laxatives can be utilized to alleviate constipation whereas taking Mounjaro, however they need to solely be taken after consulting a health care provider. Medical steerage ensures the suitable kind and dosage, stopping dependency or undesirable unwanted effects.